Chemical composition and potential bioactivities of essential oil from Quercus mongolica bark |
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| Institution: | 1. Department of Physiology, Jilin Medical University, Jilin, PR China;2. School of Pharmaceutical Sciences, Jilin University, Changchun 130012, PR China;3. The Medical Department of Neurology, Jilin Central General Hospital, Jilin 132011, PR China;4. School of Chemistry and Pharmaceutical Engineering, Jilin Institute of Chemical Technology, Jilin 132022, PR China |
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| Abstract: | The chemical composition and potential bioactivities of essential oil from Quercus mongolica bark (EOQMB) were researched for value-added utilization processing by-product. The results of gas chromatography-mass spectrometry (GC–MS) analysis showed that 30 components accounting for 98.42% were identified in EOQMB, with pentadecanoic acid the most abundant compound accounting for 34.90%, which was further confirmed by the Fourier transform infrared observation. EOQMB exerts antioxidant activities, and the IC50 values for scavenging DPPH radical, ABTS radical, and hydroxyl radical were 8.48, 0.77, and 3.54 mg/mL, respectively. The effects of EOQMB on prolonging activated partial thromboplastin time and thrombin time and on decreasing fibrinogen are similar to those of heparin, and the promising anticoagulant activities of EOQMB could be largely contributed by pentadecanoic acid. Herein, the present study uncovered that the waste Q. mongolica bark can serve as a new potential material in pharmaceutical products. |
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| Keywords: | Essential oil Chemical composition Antioxidant Anticoagulant |
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