| 1,5-二取代吡唑基-1,4-戊二烯-3-酮类化合物的合成及生物活性研究 |
| |
| 引用本文： | 王振宁,胡德禹,宋宝安,杨松,金林红,薛伟.1,5-二取代吡唑基-1,4-戊二烯-3-酮类化合物的合成及生物活性研究[J].有机化学,2009,29(9):1412-1418. |
| |
| 作者姓名： | 王振宁 胡德禹 宋宝安 杨松 金林红 薛伟 |
| |
| 作者单位： | 贵州大学精细化工研究开发中心,教育部绿色农药与农业生物工程重点实验室,贵阳,550025 |
| |
| 基金项目： | 国家科技部国际重大合作，国家自然科学基金，贵州省省长基金 |
| |
| 摘 要： | 设计合成了13个未见文献报道的1,5-二取代吡唑基-1,4-戊二烯-3-酮类化合物, 其结构经元素分析, 1H NMR, IR确证. 初步生物活性测试结果表明, 部分化合物有一定的抗烟草花叶病毒(TMV)活性, 所有化合物抑菌活性较低.
|
| 关 键 词： | 1 4-戊二烯-3-酮类衍生物 吡唑 合成 生物活性 |
| 收稿时间： | 2008-7-27 |
| 修稿时间： | 2009-1-13 |
Synthesis and Biological Activity of 1,5-Bis(substituted pyrazol-4-yl)- 1,4-pentadien-3-one Derivatives |
| |
| Wang Zhenning,Hu Deyu,Song Baoan,Yang Song,Jin Linhong,Xue Wei.Synthesis and Biological Activity of 1,5-Bis(substituted pyrazol-4-yl)- 1,4-pentadien-3-one Derivatives[J].Chinese Journal of Organic Chemistry,2009,29(9):1412-1418. |
| |
| Authors: | Wang Zhenning Hu Deyu Song Baoan Yang Song Jin Linhong Xue Wei |
| |
| Institution: | (Key Laboratory of Green Pesticide and Agriclutural Bioengineering, Ministry of Education, Research and Development
Center for Fine Chemicals, Guizhou University, Guiyang 550025)
|
| |
| Abstract: | In order to find novel anti-TMV and antifungal compounds with high activity and low toxicity, thirteen new 1,5-bis(substituted pyrazol-4-yl)-1,4-pentadien-3-one derivatives were synthesized. Their structures were characterized by IR, 1H NMR spectra and elemental analysis. Preliminary bioassays indicated that some compounds showed moderate activity against TMV, and all compounds showed weak antifungal activity. |
| |
| Keywords: | 1 |
| 本文献已被 万方数据 等数据库收录！ |
| 点击此处可从《有机化学》浏览原始摘要信息 |
| 点击此处可从《有机化学》下载免费的PDF全文 |
|
