| 3-取代和3,4-二取代噻吩的合成与表征 |
| |
| 引用本文： | 佟拉嘎,蹇锡高,王锦艳,于艳.3-取代和3,4-二取代噻吩的合成与表征[J].有机化学,2004,24(1):67-70. |
| |
| 作者姓名： | 佟拉嘎 蹇锡高 王锦艳 于艳 |
| |
| 作者单位： | 大连理工大学高分子材料系,大连,116012 |
| |
| 摘 要： | 以噻吩、48% (m/m)氢溴酸水溶液、35% (m/m)过氧化氢水溶液、高纯氨、金属钠为原料合成了3-溴噻吩和3,4-二溴噻吩,3-溴噻吩和3,4-二溴噻吩分别以(dppp)NiCl2为催化剂合成了3-烷基噻吩和3,4-二烷基噻吩.3-溴噻吩以CuI, NaHSO4为催化剂合成了3-烷氧基噻吩,产率较高.并用核磁共振谱、质谱和元素分析方法进行了表征.
|
| 关 键 词： | 噻吩衍生物 合成 表征 |
| 修稿时间： | 2003年4月21日 |
Synthesis and Characterization of 3-Substituted and 3,4-Disubstituted Thiophenes |
| |
| TONG,La-Ga JIAN,Xi-Gao WANG,Jin-Yan YU,Yan.Synthesis and Characterization of 3-Substituted and 3,4-Disubstituted Thiophenes[J].Chinese Journal of Organic Chemistry,2004,24(1):67-70. |
| |
| Authors: | TONG La-Ga JIAN Xi-Gao WANG Jin-Yan YU Yan |
| |
| Abstract: | 3-Bromothiophene and 3,4-dibromothiophene were synthesized in high yields from thiophene, 48% (m/m) aqueous hydrobromic acid, 35% (m/m) aqueous hydrogen peroxide solution, anhydrous liquid ammonia and sodium. In the presence of (dppp)NiCl 2, 3-bromothiophene and 3,4-dibromothiophene reacted with Grignard reagents to afford 3-alkylthiophene and 3,4-dialkylthiophene in good yields, respectively. 3-Alkoxythiophene was synthesized from 3-bromothiophene and alcohol using CuI and anhydrous sodium bisulfate as catalysts. The compounds obtained were characterized by 1H NMR, MS spectra and elemental analysis. |
| |
| Keywords: | thiophene derivative synthesis characterization |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
|
