| 7-芳基-10-芳基(甲基)-8, 9, 10, 11-四氢苯并[c]吖啶酮-8的 合成 |
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| 引用本文： | 韩光范,尹荣,王进军,姜贵吉.7-芳基-10-芳基(甲基)-8, 9, 10, 11-四氢苯并[c]吖啶酮-8的 合成[J].有机化学,1993,13(4):424-428. |
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| 作者姓名： | 韩光范 尹荣 王进军 姜贵吉 |
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| 作者单位： | 吉林医学院检验系，吉林化工学院精细化工系，吉林医学院检验系，延边大学化学系 吉林，吉林，132001，吉林，吉林，132022，吉林，吉林，132001，吉林，延边，133002 |
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| 摘 要： | 本工作合成了一系列尚末见报道的四环系苯基并吖啶酮类化合物。
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| 关 键 词： | 吖啶酮 杂环化合物 合成 抗癌活性 |
Synthesis of 7-phenyl-10-phenyl (methyl)-8, 9, 10, 11-tetrahydrobenz [c] acridin-8-one |
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| HAN Guang-Fan,WANG Jin-Jun,YIN Rong,JIANG Gui-Ji.Synthesis of 7-phenyl-10-phenyl (methyl)-8, 9, 10, 11-tetrahydrobenz [c] acridin-8-one[J].Chinese Journal of Organic Chemistry,1993,13(4):424-428. |
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| Authors: | HAN Guang-Fan WANG Jin-Jun YIN Rong JIANG Gui-Ji |
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| Institution: | HAN Guang-Fan,WANG Jin-Jun,YIN Rong,JIANG Gui-Ji Department of Medical Iabovatony,Jilin Medical Institute,132001 Jilin,Jilin Department of Fine Chemicals Technology,Jilin Chemical Technology Institnte,132022 Jilin,Jilin Medical Laboratory,Jilin Medical Institute,132001 Jilin,Jilin Department of Chemistry,Yanbian University,133002 Yanji,Jilin |
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| Abstract: | Hexahydrobenzc]cridin-8-ones were synthesized from cgclicdiketone, α-naphthylamine and appropriate aromatic aldehydes in ethanol. Oxidation of the hexahydro-benzc]acridin-8-one with chromic anhydride in acetic acid affordes tetrahydrobenzc]acridin-8-one. |
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| Keywords: | acridone heterocyclic compounds synthesis anticancer activity |
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