| 微波辅助一步合成2-取代吲哚 |
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| 引用本文： | 陈静,胡永洲.微波辅助一步合成2-取代吲哚[J].有机化学,2006,26(7):996-1000. |
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| 作者姓名： | 陈静 胡永洲 |
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| 作者单位： | 浙江大学药学院药物化学教研室,杭州,310031 |
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| 摘 要： | 微波辐射下以取代苯胺1, 2-溴芳基乙酮2为原料, 在无催化剂条件下一步合成了一系列2-取代吲哚3. 该方法具操作简单、反应时间短、产率高等特点.
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| 关 键 词： | 苯胺 2-溴芳基乙酮 微波辐射 吲哚 |
| 收稿时间： | 10 19 2005 12:00AM |
| 修稿时间： | 2005-10-192006-01-23 |
Microwave-Assisted One-Pot Synthesis of 2-Substituted Indoles |
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| CHEN Jing,HU Yong-Zhou.Microwave-Assisted One-Pot Synthesis of 2-Substituted Indoles[J].Chinese Journal of Organic Chemistry,2006,26(7):996-1000. |
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| Authors: | CHEN Jing HU Yong-Zhou |
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| Institution: | Department of Medicinal Chemistry, School of Pharmaceutical Science, Zhejiang University, Hangzhou 310031 |
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| Abstract: | A series of 2-substituted indoles 3 were synthesized using substituted aniline 1 and 2-bromoace- tophenone 2 as starting materials under microwave irradiation conditions without any catalysts. The reac- tions were easily worked up with short time and high yields. |
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| Keywords: | aniline 2-bromoacetophenone microwave irradiation indole |
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