| 树枝状化合物作为药物载体的研究进展 |
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| 引用本文： | 何谷,郭丽.树枝状化合物作为药物载体的研究进展[J].有机化学,2008,28(8):1326-1335. |
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| 作者姓名： | 何谷 郭丽 |
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| 作者单位： | 四川大学华西药学院药物化学系,靶向药物教育部重点实验室,成都,610041 |
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| 摘 要： | 树枝状化合物是一类具有规整结构和单分散性的大分子化合物, 具有不同于普通高分子化合物的独特理化性质, 广泛地应用在材料、催化以及生物医学领域中. 简要综述了树枝状化合物作为药物载体及其在抗病毒、抗肿瘤以及多肽和糖模拟物等领域的研究进展.
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| 关 键 词： | 树枝状化合物 药物载体 抗病毒 抗肿瘤 肽模拟物 |
| 收稿时间： | 2007-5-9 |
| 修稿时间： | 2007-10-8 |
Progress in Dendrimers as Drug Carriers |
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| HE,Gu,GUO,Li.Progress in Dendrimers as Drug Carriers[J].Chinese Journal of Organic Chemistry,2008,28(8):1326-1335. |
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| Authors: | HE Gu GUO Li |
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| Institution: | (Key Laboratory of Drug Targeting of Ministry of Education, Department of Medicinal Chemistry,
West China School of Pharmacy, Sichuan University, Chengdu 610041)
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| Abstract: | Dendrimers are monodisperse macromolecules with strict structures, which have a lot of unique physical and chemical characteristics different from normal polymers and widely applicated to the material, catalyst and biomedical areas. Dendrimers as drug carriers and their applications to the areas of antiviral, anti-tumor, peptide and saccharide analogues are discussed. |
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| Keywords: | dendrimer drug carrier antiviral anti-tumor peptide analogue |
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