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Phase Transfer Catalyzed Synthesis under Ultrasonic Irradiation and Bioactivity of N'-(4,6-Disubstituted-pyrimidin-2-yl)-N-(5-aryl-2-furoyl) Thiourea Derivatives
作者姓名:KE  Shao-Yong  WEI  Tai-Bao  XUE  Si-Jia  DUAN  Li-Ping  GUO  Yan-Ling
作者单位:KE,Shao-Yong(Department of Chemistry, Shanghai Normal University, Shanghai 200234)  WEI,Tai-Bao(Department of Chemistry, Northwest Normal University, Lanzhou 730070)  XUE,Si-Jia(Department of Chemistry, Shanghai Normal University, Shanghai 200234)  DUAN,Li-Ping(Department of Chemistry, Shanghai Normal University, Shanghai 200234)  GUO,Yan-Ling(Department of Chemistry, Shanghai Normal University, Shanghai 200234)
摘    要:Acylthiourea derivatives are useful as pesticides, herbicides, fungicides and regulator for plant growth, and also as important intermediates in the organic synthesis. In recent years, phase transfer catalysis reaction technique has been widely recognized as an efficient synthetic tool and attracted much attention. In view of these observations, a series of 5-aryl-2-furoyl thioureas containing substituted pyrimidine ring were synthesized using PEG-400 as solid-liquid phase transfer catalyst under ultrasonic irradiation. All of the new compounds have been exactly determined by IR, 1H NMRand elemental analysis.


Phase Transfer Catalyzed Synthesis under Ultrasonic Irradiation and Bioactivity of N'-(4,6-Disubstituted-pyrimidin-2-yl)-N-(5-aryl-2-furoyl) Thiourea Derivatives
KE,Shao-Yong,WEI Tai-Bao,XUE,Si-Jia,DUAN,Li-Ping,GUO,Yan-Ling.Phase Transfer Catalyzed Synthesis under Ultrasonic Irradiation and Bioactivity of N''''-(4,6-Disubstituted-pyrimidin-2-yl)-N-(5-aryl-2-furoyl) Thiourea Derivatives[J].Chinese Journal of Organic Chemistry,2004,24(Z1):237-238.
Authors:KE  Shao-Yong  WEI Tai-Bao  XUE  Si-Jia  DUAN  Li-Ping  GUO  Yan-Ling
Abstract:Acylthiourea derivatives are useful as pesticides, herbicides, fungicides and regulator for plant growth, and also as important intermediates in the organic synthesis. In recent years, phase transfer catalysis reaction technique has been widely recognized as an efficient synthetic tool and attracted much attention. In view of these observations, a series of 5-aryl-2-furoyl thioureas containing substituted pyrimidine ring were synthesized using PEG-400 as solid-liquid phase transfer catalyst under ultrasonic irradiation. All of the new compounds have been exactly determined by IR, 1H NMRand elemental analysis.
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