|
|||||
|
|
| 水介质中4-芳基-3-甲基-1-苯基-4,5,6,7,8,9-六氢化吡唑并[5,4-b]喹啉-5-酮衍生物的三组分一锅合成 | |
| 引用本文： | 史达清,拾景文,姚浩,蒋虹,王香善.水介质中4-芳基-3-甲基-1-苯基-4,5,6,7,8,9-六氢化吡唑并[5,4-b]喹啉-5-酮衍生物的三组分一锅合成[J].有机化学,2008,28(2):261-265. |
| 作者姓名： | 史达清 拾景文 姚浩 蒋虹 王香善 |
| 作者单位： | 1. 苏州大学化学化工学院,江苏省有机合成重点实验室,苏州,215123;徐州师范大学化学系,徐州,221116;江苏省药用植物生物技术重点实验室,徐州,221116 2. 徐州师范大学化学系,徐州,221116 3. 江苏省药用植物生物技术重点实验室,徐州,221116 4. 徐州师范大学化学系,徐州,221116;江苏省药用植物生物技术重点实验室,徐州,221116 |
| 基金项目： | 江苏省教育厅青蓝工程项目，江苏省重点实验室基金 |
| 摘 要： | 在水介质中有十二烷基磺酸钠(SDS)存在下, 以芳醛、5-氨基-3-甲基-1-苯基吡唑、1,3-环己二酮三组分一锅反应合成了4-芳基-3-甲基-1-苯基-4,5,6,7,8,9-六氢化吡唑并5,4-b]喹啉-5-酮衍生物, 产物的结构通过IR, 1H NMR确证, 化合物4e的结构经单晶X射线衍射确证. |
| 关 键 词： | 4 5 6 7 8 9-六氢化吡唑并[5 4-b]喹啉-5-酮 三组分 水介质 一锅合成 |
| 收稿时间： | 2007-01-17 |
| 修稿时间： | 2007-09-07 |
Three-Component One-Pot Synthesis of 4-Aryl-3-methyl-1-phenyl- 4,5,6,7,8,9-hexahydropyrazolo[5,4-b]quinolin-5-one Derivatives in Aqueous Media |
|
| SHI Da-Qing,SHI Jing-Wen,YAO Hao,JIANG Hong,WANG Xiang-Shan.Three-Component One-Pot Synthesis of 4-Aryl-3-methyl-1-phenyl- 4,5,6,7,8,9-hexahydropyrazolo[5,4-b]quinolin-5-one Derivatives in Aqueous Media[J].Chinese Journal of Organic Chemistry,2008,28(2):261-265. | |
| Authors: | SHI Da-Qing SHI Jing-Wen YAO Hao JIANG Hong WANG Xiang-Shan |
| Institution: | (Key Laboratory of Organic Synthesis of Jiangsu Province, College of Chemistry and Chemical En-gineering,Suzhou University, Suzhou 215123)(Department of Chemistry, Xuzhou Normal University, Xuzhou 221116)(Key Laboratory of Biotechnology on Medical Plants of Jiangsu Province, Xuzhou 221116) |
| Abstract: | 4-Aryl-3-methyl-1-phenyl-4,5,6,7,8,9-hexahydropyrazolo5,4-b]quinolin-5-one derivatives were synthesized by a three-component one-pot reaction of aromatic aldehydes, 5-amino-3-methyl-1- phenylpyrazole and 1,3-cyclohexanedione using sodium dodecanesulfonate (SDS) as a catalyst in aqueous media. The structures of products were identified by IR and 1H NMR spectra, and the structure of 4e was confirmed by X-ray diffractional analysis. |
| Keywords: | 4 5 6 7 8 9-hexahydropyrazolo[5 4-b]quinolin-5-one three-component aqueous media one-pot synthesis |
| 本文献已被 维普 万方数据 等数据库收录！ | |
| 点击此处可从《有机化学》浏览原始摘要信息 | |
| 点击此处可从《有机化学》下载免费的PDF全文 | |