| 4-羟基-2-吡啶酮类化合物的合成研究进展 |
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| 引用本文： | 赵圣印,黄婧,程健,刘宝硕,陈晨.4-羟基-2-吡啶酮类化合物的合成研究进展[J].有机化学,2012(4):651-660. |
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| 作者姓名： | 赵圣印 黄婧 程健 刘宝硕 陈晨 |
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| 作者单位： | 东华大学化学化工与生物工程学院 上海201620 |
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| 基金项目： | 上海市自然科学基金，国家自然科学基金 |
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| 摘 要： | 4-羟基-2-吡啶酮是天然生物碱结构母核,同时也是一类重要的医药中间体,该类衍生物具有抗真菌、抗菌和抗肿瘤等多种生物活性.因此,其合成得到了广泛的研究和关注.综述了近年来4-羟基-2-吡啶酮类化合物的合成方法及其研究进展.
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| 关 键 词： | 4-羟基-2-吡啶酮 合成 研究进展 |
Progress in the Synthesis of 4-Hydroxy-2-pyridone Derivatives |
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| Zhao, Shengyin
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Huang, Jing
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Cheng, Jian
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Liu, Baoshuo
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Chen, Chen.Progress in the Synthesis of 4-Hydroxy-2-pyridone Derivatives[J].Chinese Journal of Organic Chemistry,2012(4):651-660. |
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| Authors: | Zhao Shengyin Huang Jing Cheng Jian Liu Baoshuo Chen Chen |
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| Institution: | Zhao,Shengyin Huang,Jing Cheng,Jian Liu,Baoshuo Chen,Chen(College of Chemistry,Chemical Engineering & Biotechnology,Donghua University,Shanghai 201620) |
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| Abstract: | 4-Hydroxy-2-pyridones are embedded as common structural units of many natural products,which exhibited good or excellent biological activities such as antifungal,antibacterial,and cytototoxic activity and so on.The class of compounds has stimulated a great deal of interest on synthetic chemists due to their structural novelty,molecular diversity,and promising biological activities.In this paper,the recent progress in the synthesis of 4-hydroxy-2-pyridones has been reviewed. |
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| Keywords: | 4-hydroxy-2-pyridone synthesis research progress |
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