2-芳氧基-5-苯基-1,3,4-恶二唑类化合物的合成

通过芳氧基负离子在2-甲磺酰基-5-1,3,4-恶二唑上的亲核取代反应制得2-芳氧基-5-苯基-1,3,4-恶二唑.所有化合物的结构经元素分析,IR, ^1H NMR和MS确证.这些化合物表现出一定的抑制枯草芽孢杆菌繁殖的活性.

Synthesis of 2-aryloxy-5-phenyl-1,3,4-oxadiazoles

2-aryloxy-5-phenyl-1,3,4-oxadiazole had been prepared via nucleophilic substitution of 2- methylsulphonyl-5-phenyl-1,3,4-oxadiazole by aryloxy anion. Their structures were characterized by elemental analyses, IR, MS and ^1HNMR spectra. These compounds showed some inhibiting activity on B. Subtilis.