固相同步多重肽合成

本文综述了近十年来在固相肽合成基础上发展的各种同步多重合成新技术。它们的应用可进一步提高肽合成的效率、降低成本,并将促进许多肽的结构-活性关系研究。因此,将对激素-受体间作用的机理研究、对分子免疫学的发展及研究新的肽类诊断试剂或疫苗均可创造较好的条件。

Solid phase simultaneous multiple peptide synthesis

Simultaneous multiple peptide synthesis (SMPS), a recently developed technology in solid phase peptide synthesis (SPPS) has considerably speeded up the synthetic procedure. It is obvious that SMPS is a great help to promote the researches of hormone-receptor interaction and of molecular immunology and to develop some new diagnostic reagents and synthetic vaccines.