可见光直接促进的过渡金属催化交叉偶联反应研究进展

经过几十年的发展,过渡金属催化的交叉偶联反应已经成为一类功能强大的有机合成方法,广泛应用于各种碳碳键和碳杂原子键的高效构建.最近几年化学家们发现在越来越多的情况下,不用外加光敏剂,可见光能直接促进过渡金属催化的交叉偶联反应,使原来无法发生或缓慢进行的偶联反应得以顺利实现.该类反应因条件简单、反应温和以及无需外加光敏剂等优点受到了广泛的关注.根据过渡金属的分类,综述了近些年来该类反应的研究进展.

Rece nt Advances in Tran sition Metal-Catalyzed Cross-Coupli ng Reactions Directly Promoted by Visible Light

Over the last decades,the transition metal-catalyzed cross-coupling reactions have become powerful organic synthetic methods for forming carbon-carbon and carbon-heteroatom bonds.Very recently,the introduction of visible light into transition metal catalysis opened a new avenue for achieving novel,highly enabling cross-coupling reactions that otherwise were elusive.This type of reaction has received extensive attention due to its simple,mild conditions and no need of photocatalyst.Based on the classification of transition metals,the research progress of transition metal-catalyzed cross-coupling reactions directly promoted by visible light is reviewed.