基于纳米金增敏的双酚A二氧化钛凝胶分子印迹电化学传感器的制备及应用

以纳米金(Au NPs)为增敏材料,双酚A(BPA)为模板分子,结合表面溶胶凝胶法和自组装法,制备了BPA纳米金-Ti O_2凝胶分子印迹电化学传感器。利用扫描电子显微镜和能谱对Au NPs进行了表征,利用红外光谱仪对Ti O_2凝胶、BPA以及BPA印迹Ti O_2凝胶进行表征。在最优条件下,该传感器对BPA在1.0×10~(-8)~1.0×10~(-5)mol/L浓度范围内具有良好的线性关系,线性相关系数为0.995,检测限为0.6×10~(-8)mol/L,并将该分子印迹传感器应用于实际样品中BPA的分析检测,其回收率为97.4%~103%。

Preparation and Application of Bisphenol-A TiO2 Gel Molecularly Imprinted Electrochemical Sensor Based on the Sensitivity-Enhancement of Gold Nanoparticles

A bisphenol-A(BPA) TiO₂ gel molecularly imprinted electrochemical sensor was fabricated using gold nanoparticles(AuNPs) as sensitivity-enhanced materials based on surface sol-gel and self-assembly methods. AuNPs were characterized by scanning electron microscopy(SEM) and energy dispersive spectroscopy. BPA, TiO₂ gel, and BPA-imprinted TiO₂ gel were characterized by Fourier transform infrared(FTIR) spectrometry. Under optimal conditions, the sensor exhibits a good linear response from 1.0×10^-8 to 1.0×10^-5 mol/L for bisphenol A, with correlation coefficient 0.995 and a low detection limit of 0.6×10^-8 mol/L(S/N=3). The prepared sensor was successfully applied in the detection of actual sample with 97.4%~103% recoveries.