| 杂多配合物抗狐脑炎病毒的活性探讨 |
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| 引用本文： | 刘杰,王丽君,梅文杰,刘建忠,王恩波,计亮年.杂多配合物抗狐脑炎病毒的活性探讨[J].应用化学,2000,17(5):495-0. |
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| 作者姓名： | 刘杰 王丽君 梅文杰 刘建忠 王恩波 计亮年 |
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| 作者单位： | 中山大学，吉林医学院，东北师范大学 |
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| 基金项目： | 国家自然科学基金! (39870 895 )，国家新药基金!(96 - 90 1- 0 5 - 15 8)资助项目 |
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| 摘 要： | 抗病毒活性;杂多配合物抗狐脑炎病毒的活性探讨
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| 关 键 词： | 抗病毒活性 杂多配合物抗狐脑炎病毒的活性探讨 |
| 收稿时间： | 2009-06-29 |
| 修稿时间： | 2009-06-29 |
Activity of Heteropoly Compounds for Anti-Fox encephalitis Virus |
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| LIU Jie,WANG Li-Jun,MEI Wen-Jie,LIU Jian-Zhong,WANG En-bo,JI Liang-Nian.Activity of Heteropoly Compounds for Anti-Fox encephalitis Virus[J].Chinese Journal of Applied Chemistry,2000,17(5):495-0. |
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| Authors: | LIU Jie WANG Li-Jun MEI Wen-Jie LIU Jian-Zhong WANG En-bo JI Liang-Nian |
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| Abstract: | Ten heteropoly compounds were synthesized. Their toxicity to the cells of dog kidney and activity for anti-fox encephalitis virus at nontoxic concentrations were tested by cell culture method. Some of the compounds had high anti-FEV activity at nontoxic concentration, among them HPC-9 had IC_50 of 8 mg/L, TC_50 of 530 mg/L and TI of 66. The antivirus mechanism of the compounds has been discussed briefly. |
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| Keywords: | heteropoly compound antivirus activity fox encephalitis virus |
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