多壁碳纳米管修饰玻碳电极测定乙炔雌二醇

多壁碳纳米管修饰玻碳电极测定乙炔雌二醇;多壁碳纳米管;乙炔雌二醇;化学修饰电极;电化学测定

Voltammetric Determination of Ethynylestradiol Using Multi-wall Carbon Nanotube Modified Glassy Carbon Electrode

An electrochemical method was developed for the determination of ethynylestradiol based on the electrocatalytic activity of multi-wall carbon nanotube(MWNT). Owing to the unique and extraordinary pro-(perties) of MWNT, the oxidation peak current of ethynylestradiol increases remarkably on a MWNT-modified glassy carbon electrode(GCE), accompanied by the lowering of oxidation overpotential. The oxidation peak current varies linearly with the concentration of ethynylestradiol in the range from 110~(-7) to 410~(-5) mol/L. The detection limit is 310~(-8) mol/L after open-circuit accumulation for 3 min. The relative standard (deviation)(RSD) of ten measurements is 6.2% for 110~(-6) mol/L ethynylestradiol, indicating the good reproducibility. This proposed method was successfully employed in detecting ethynylestradiol in ethynylestradiol tablets.