| Bronsted酸催化合成α-氨基膦酸酯 |
| |
| 引用本文： | 姚元勇,吴兰艳,舒华,唐帮成,薛伟.Bronsted酸催化合成α-氨基膦酸酯[J].应用化学,2014,31(12):1428-1433. |
| |
| 作者姓名： | 姚元勇 吴兰艳 舒华 唐帮成 薛伟 |
| |
| 作者单位： | (1.铜仁学院生物与化学工程系，梵净山特色动植物资源重点实验室 铜仁 554300；
2.贵州大学精细化工研究中心 贵阳 550025) |
| |
| 基金项目： | 贵州省教育厅“125”重大科技专项([2012]018);贵州省教育厅联合基金KY字[2011]005;铜仁市科技局自然科学基金[2014]40-3~~ |
| |
| 摘 要： | 以芳香胺和肉桂醛为原料，合成的芳香族亚胺为亲电试剂，亚磷酸二乙酯或亚磷酸三乙酯为亲核试剂，在10%（摩尔分数）磷酸催化剂（Bronsted acid）的作用下，通过催化剂与亲电试剂、亲核试剂之间共同形成的双氢键或单氢键的作用，成功地合成了α-氨基膦酸酯类化合物，收率可达到79%～85%。
|
| 关 键 词： | Bronsted酸 &alpha -氨基膦酸酯 氢键作用 催化 磷氢化反应 |
| 收稿时间： | 2014-02-25 |
| 修稿时间： | 2014-06-16 |
Synthesis of α-Aminophosphonates by Bronsted Acid Catalysis |
| |
| YAO Yuanyong;WU Lanyan;SHU Hua;TANG Bangcheng;XUE Wei.Synthesis of α-Aminophosphonates by Bronsted Acid Catalysis[J].Chinese Journal of Applied Chemistry,2014,31(12):1428-1433. |
| |
| Authors: | YAO Yuanyong;WU Lanyan;SHU Hua;TANG Bangcheng;XUE Wei |
| |
| Institution: | (1.Department of Biological and Chemical Engineering,Fanjing Mountain Key Laboratory of ;
Special Animal and Plant Resource,Tongren University,Tongren 554300,China;
2.Center for Research & Development of Fine Chemicals,Guizhou University,Guiyang 550025,China) |
| |
| Abstract: | Electrophilic aromatic imines synthesized by the condensation of aromatic amines with cinnamyl aldehyde were allowed to react with diethyl phosphite or triethyl phosphite as nucleophile in the presence of 10% molar fraction of phosphoric acid(Bronsted acid). The α-aminophosphonate derivatives were obtained through binary or single hydrogen bonding interaction of catalyst with nucleophiles and electrophiles in up to 79%~85% yields. |
| |
| Keywords: | Bronsted acid α-aminophosphonate hydrogen bonding interaction catalysis hydrophosphonylation |
| 本文献已被 CNKI 等数据库收录！ |
| 点击此处可从《应用化学》浏览原始摘要信息 |
| 点击此处可从《应用化学》下载免费的PDF全文 |
