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低硒克山病病区和非病区居民红细胞免疫功能的对比测定
引用本文:张培毅,梁文升.低硒克山病病区和非病区居民红细胞免疫功能的对比测定[J].广东微量元素科学,1998,5(7):14-16.
作者姓名:张培毅  梁文升
作者单位:西安医科大学微量元素与地方病研究实验室!西安,710061,西安医科大学微量元素与地方病研究实验室!西安,710061,西安医科大学微量元素与地方病研究实验室!西安,710061,西安医科大学微量元素与地方病研究实验室!西安,710061,西安医科大学微量元素与地方病研究实验室!西安,71
摘    要:对比测定了低硒克山病病区和非病区居民的红细胞免疫功能、血清红细胞免疫粘附调节因子和血硒含量。结果表明,低硒病区和非病区居民红细胞C3bR花环率和血硒水平显著低于对照非病区,而血清红细胞免疫粘附花环抑制率显著高于对照非病区;3组居民的红细胞免疫复合物花环率和血清红细胞免疫粘附花环促进率无明显差异;低硒病区和非病区居民上述各参数值均相似。研究说明,克山病病区居民红细胞免疫功能低下和血清红细胞免疫粘附抑

关 键 词:红细胞  硒缺乏  克山病  免疫功能  测定

Contrastive Determination on Erythrocyte on Function of Residents in Selenium-Deficient Keshan Disease Endemic and Non-endemic Areas
Zhang Peiyi, hang Wensheng, Xu Guanglu et al.Contrastive Determination on Erythrocyte on Function of Residents in Selenium-Deficient Keshan Disease Endemic and Non-endemic Areas[J].Trace Elements Science,1998,5(7):14-16.
Authors:Zhang Peiyi  hang Wensheng  Xu Guanglu
Abstract:The erythrocyte immune function, serum erythrocyte immune adherence regulatory factors andblood selenium content were comparatively determined of die residents in the low selenium Keshan diseaseendemic and nonendemic areas. The results showed that the rosette formation rates of erythrocyte C(3b)R andblood selenium levels of the residents in both the low selenium areas were significantly lower and the rosetteforming inhibitory rates of serum erythrocyte immune adherence were higher than those of the residents inthe control non-endemic area. No remarkable differences were observed between the rosette formationrate of erythrocyte immune complex and rosette forming promotive rate of serum erythrocyte immune adherence among the three groups, and the values of all the Parameters mentioned above of the residents fromboth the low. selenium areas were comparable to each other. The study demonstrates that the decrease ofthe erythrocyte immune function and the enhancement of the serum rosette forming inhibiting rate of the residents in the Keshan disease endemic area result from the low selenium status and are not specific to thedisease.
Keywords:Erythrocyte  Immunity  Selenium deficiency  Keshan disease
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