| 老年痴呆症患者头发中微量元素含量变化及其临床意义 |
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| 引用本文： | 徐美奕,陈素珍,关雄泰,郑泽荣,廖晓岚.老年痴呆症患者头发中微量元素含量变化及其临床意义[J].广东微量元素科学,2001,8(8):20-23. |
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| 作者姓名： | 徐美奕 陈素珍 关雄泰 郑泽荣 廖晓岚 |
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| 作者单位： | 1. 广东医学院分析中心
2. 湛江市第二中医院 |
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| 摘 要： | 应用火焰原子吸收分光光度法测定了30例老年痴呆症患者及34例健康老人发中Zn、Cu、Fe、Ca、Pb、Cd的含量。结果表明，老年痴呆症组发Zn、Fe、Ca显著低于健康组（P＜0．01），Pb、Cd显著高于健康组（P＜0．01），且Cd/Zn比值显著高于健康组，有非常显著的差异（P＜0．001）。结果提示，老年痴呆症的发生可能与Zn、Ca、Pb、Cd等微量元素的含量水平异常有关，Cd/Zn比值升高可能是老年痴呆症发生的危险因素之一。
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| 关 键 词： | 老年痴呆症 头发 微量元素 火焰原子吸收分子光光度法 含量变化 临床意义 |
| 文章编号： | 1006-446(2001)08-0020-04 |
| 修稿时间： | 2001年6月20日 |
Change of Trace Elements Content in Hair of Patients with Senile Dementia and Its Clinical Significance |
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| XU Mei-yi ,CHEN Su-zhen ,GUAN Xiong-tai ,ZHENG Ze-rong ,LIAO Xiao-lan.Change of Trace Elements Content in Hair of Patients with Senile Dementia and Its Clinical Significance[J].Trace Elements Science,2001,8(8):20-23. |
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| Authors: | XU Mei-yi CHEN Su-zhen GUAN Xiong-tai ZHENG Ze-rong LIAO Xiao-lan |
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| Institution: | XU Mei-yi 1,CHEN Su-zhen 1,GUAN Xiong-tai 1,ZHENG Ze-rong 2,LIAO Xiao-lan 2 |
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| Abstract: | The content of Zn,Cu,Fe,Ca,Pb,Cd in hair of 30 patients with senile dementia and that of 34 healthy old men was determined by FAAS.The results showed that the content of Zn,Fe,Ca in senile dementia group was significantly lower than healthy group(P<0.01).The content of Pb,Cd in senile dementia group was significantly higher than that of healthy group(P<0.01),and the ratio of Cd/Zn in senile dementia group was very significantly higher than that of healthy group(P<0.001).It concluded that senile dementia might be related to the abnormal levels of trace elements of Zn,Ca,Pb,Cd,and the increase in the ratio of Cd/Zn may be a dangerous factor for senile dementia. |
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| Keywords: | senile dementia hair trace element FAAS |
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