高氟铝和铝引起低龄鸡骨发育不全

进行了高氟铝和铝对低龄鸡骨损害的实验。５７日龄鸡９６只随机分为８组，毒物加进饲料，实验期３个月。结果表明，各高氟、高氟铝组骨氟均数倍于对照组，低铝组骨氟显著升高；单饲ＮａＦ组骨铝增高近３倍，高氟铝组骨氟比ＮａＦ组和病区玉米组低１／３以上，骨铝低约５０％；单饲铝达对照４～２１倍的骨铝与对照组接近。饲氟与骨氟ｒ＝０．７７，与骨铝ｒ＝０．６５；饲铝与骨铝ｒ＝－０．４６，与骨氟ｒ＝－０．５３；骨氟与骨铝ｒ

An Experimental Study on Osteopathia of Young Cocks with Al-F Toxicosis

cocks of 57 days were randomly divided into 8 groups and fed with mixture of feed and toxicants for 3 months.The results showed that bone F content of high F and high F-Al groups were several times higher than that of controls.Bone F in low Al groups increased markedly. Bone Al in simple NaF groups increased by 3 times.Bone F of high F-Al groups was 1/3 lower than that of NaF groups and groups fed on corn from Al-F toxicosis areas,while hone Al was 50% lower.The bone Al of 3 high Al groups was close to that of controls. The correlation coefficients r of F taken with bone F,F taken with bone Al,Al taken with bone Al,Al taken with bone F,and bone F with bone Al were 0 71,0 65,-0 46,-0 53 and 0 98 respectively. Brain Al, liver Al,and kidney Al of treated groups were increased, especially in the groups fed on food with Al salt.There was a reduction of volume of bone lamella and osteoid,but the area and the width of them increased markedly.The numbers of osteoblasts and osteoclast reduced and the double mark of tetracycline diffused,which suggested that Al could limitedly reduce high F.While F would improve the accumulation of Al in bones.But under the conditions of high content of F-Al,Al accumulation in bones decreased markedly and the content of other bone elements changed to different degrees in the same time.As another kind of osteopathia and the disturbance of mine deposition,the osteopathological manifestation of these experimental cocks differed from those osteomalcia cocks of 100 days.