| AGE-DEPENDENT LOGISTIC REGRESSION MODEL AND ITS APPLICATION |
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| 引用本文： | 刘韵源. AGE-DEPENDENT LOGISTIC REGRESSION MODEL AND ITS APPLICATION[J]. 中国科学B辑(英文版), 1991, 0(4) |
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| 作者姓名： | 刘韵源 |
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| 作者单位： | Cancer Institute，Chinese Academy of Medical Sciences，Beijing 100021，PRC |
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| 摘 要： | In the present paper we introduce the theory and algorithm of the unconditional and con-ditional age-dependent logistic regression model, which combines logistic regression analysisof case-control study with survival analysis of cases in the data, thus facilitating simulta-neous comparison analysis between cases and controls and among cases with different ages ofdisease onset under study. In age-dependent logistic regression analysis, estimated compoundrelative risk (CRR) and compound attributable risk (CAR)comprise the variance contribu-tions of risk factors to disease occurrence and the time of disease onset, thereby the roleplayed by various risk factors in etiology and etiopathology can be objectively evaluated.The current logistic regression model is only a particular case of age-dependent logistic re-gression theory neglecting the variations in onset age of diseases.
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AGE-DEPENDENT LOGISTIC REGRESSION MODEL AND ITS APPLICATION |
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| LIU YUN-YUAN Cancer Institute,Chinese Academy of Medical Sciences,Beijing ,PRC. AGE-DEPENDENT LOGISTIC REGRESSION MODEL AND ITS APPLICATION[J]. Science in China(Chemistry), 1991, 0(4) |
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| Authors: | LIU YUN-YUAN Cancer Institute Chinese Academy of Medical Sciences Beijing PRC |
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| Affiliation: | LIU YUN-YUAN Cancer Institute,Chinese Academy of Medical Sciences,Beijing 100021,PRC |
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| Abstract: | In the present paper we introduce the theory and algorithm of the unconditional and con-ditional age-dependent logistic regression model, which combines logistic regression analysisof case-control study with survival analysis of cases in the data, thus facilitating simulta-neous comparison analysis between cases and controls and among cases with different ages ofdisease onset under study. In age-dependent logistic regression analysis, estimated compoundrelative risk (CRR) and compound attributable risk (CAR)comprise the variance contribu-tions of risk factors to disease occurrence and the time of disease onset, thereby the roleplayed by various risk factors in etiology and etiopathology can be objectively evaluated.The current logistic regression model is only a particular case of age-dependent logistic re-gression theory neglecting the variations in onset age of diseases. |
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| Keywords: | As-logistic regression Ad-logistic regression proportional odds model cox regression compound relative risk compound attributable risk adjusted attributable risk summary attributable risk |
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