|
|||||
|
|
| SYNTHESIS OF METHYLISOAMYLNITROSAMINE FROM ISOAMYLAMINE BY FUNGI(FUSARIUM MONILIFORME) | |
| 作者姓名： | 季川 李铭新 李金兰 赵守金 王光辉 贺玉珍 |
| 作者单位： | Department of Chemical Etiology and Carcinogenesis，Cancer Institute，Chinese Academy of Medical Sciences，Beijing，Department of Chemical Etiology and Carcinogenesis，Cancer Institute，Chinese Academy of Medical Sciences，Beijing，Department of Chemical Etiology and Carcinogenesis，Cancer Institute，Chinese Academy of Medical Sciences，Beijing，Department of Chemical Etiology and Carcinogenesis，Cancer Institute，Chinese Academy of Medical Sciences，Beijing，Department of Chemical Analysis，Institute of Chemistry，Academia Sinica，Beijing，Department of Chemical Analysis，Institute of Chemistry，Academia Sinica，Beijing |
| 摘 要： | Methylisoamylnitrosamine, a carcinogenic N-nitroso compound, has been formed in glucose ammonium nitrate medium containing 150 mg of isoamylamine (a primary amine) inoculated with a common fungus (Fusarium moniliforme Sheldon), to which 400 mg NaNO_2 are added after incubation for 7—8 days at 28℃. No such compound has been found in control samples without fungi or isoamylamine. This paper reports a method of experimental synthesis of the nitrosamine by F. moniliforme strains 82—01 and 83—01, using isoamylamine and NaNO_2, as well as the analysis of the compound by GC/MS and GC/TEA. |
| 本文献已被 CNKI 等数据库收录！ | |