| 荧光光谱法研究利血平的氧化作用及其分析应用 |
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| 引用本文： | 张丽瑶,黄春保,杨洗,潘祖亭.荧光光谱法研究利血平的氧化作用及其分析应用[J].分析科学学报,2000,16(6):466-469. |
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| 作者姓名： | 张丽瑶 黄春保 杨洗 潘祖亭 |
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| 作者单位： | 武汉大学化学系，武汉，430072 |
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| 摘 要： | 利血平自身有弱荧光，氧化后可形成较强荧光物质。本文系统地研究了稀ＨＮＯ３对利血平的氧化作用，提出了高灵敏度测定利血平含量的荧光光度分析新方法。结果表明，荧光强度和利血平的浓度在０．０２－０．４μｇ／ｍＬ范围内呈良好的线性关系，方法的检出限为０．００２μｇ／ｍＬ（６．７３＊１０＾－９ｍｏｌ／Ｌ）。该法简便，快速、灵敏度高，用于注射液中利血平含量的测定，结果令人满意。
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| 关 键 词： | 荧光光谱法 利血平 药物分析 氧化法 降压药 |
| 文章编号： | 1006-6144(2000)06-0466-04 |
| 修稿时间： | 2000年2月22日 |
Studies on the Oxidation Reaction of Reserpine by Spectrofluorimetry and Its Analytical Application |
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| ZHANG Li-yao,HUANG Chun-bao,YANG Xi,Pan Zu-ting.Studies on the Oxidation Reaction of Reserpine by Spectrofluorimetry and Its Analytical Application[J].Journal of Analytical Science,2000,16(6):466-469. |
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| Authors: | ZHANG Li-yao HUANG Chun-bao YANG Xi Pan Zu-ting |
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| Institution: | ZHANG Li yao,HUANG Chun bao,YANG Xi,PAN Zu ting * |
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| Abstract: | Reserpine, a lowly fluorescent substance, can be trans formed into a highly fluorescent product by oxidation. The oxidation reaction of reserpine was studied and a high sensitive fluorimetric method for the determin ation of reserpine was developed. The linear relationship between the fluorescen ce intensity and the concentration of reserpine was over the range of 0.02～0.4 μg/mL. The method has been applied to the determination of reserpine in the in jection with satisfactory results. |
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| Keywords: | Spectrofluorimetry Reserpine Pharmaceutial analysis Oxidation reaction |
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