| 高稳定性黑米碳点的绿色合成及其细胞成像应用 |
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| 引用本文： | 张清梅,张路鹏,郑开文,杨国庆,何松杰,杜秀娟,陈峰华,李冰.高稳定性黑米碳点的绿色合成及其细胞成像应用[J].无机化学学报,2013,29(18). |
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| 作者姓名： | 张清梅 张路鹏 郑开文 杨国庆 何松杰 杜秀娟 陈峰华 李冰 |
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| 作者单位： | 太原科技大学应用科学学院, 太原 030024;山西医科大学口腔医学院, 太原 030001 |
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| 基金项目： | 国家自然科学基金(No.11704274)、 山西省自然科学基金(No.201901D111267)和山西省领军人才计划(No.20190042)资助。 |
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| 摘 要： | 以绿色廉价的黑米为碳源，采用简单的水热法一步合成了碳点(carbon dots，CDs)。所合成的CDs不仅对pH、NaCl溶液和温度变化不敏感，并且不受多种金属离子的影响，表现出优异的稳定性。同时，CDs在较短波长范围(410~470 nm)表现出激发不依赖的发射行为，在较长波长范围(470~510 nm)又表现出弱激发依赖的发射行为。由于其优异的荧光特性、稳定性和低毒性，我们将其应用于人口腔角质形成细胞(Hok)、宫颈癌细胞(Hela)和骨髓间充质干细胞(MC3T3)的体外成像。
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| 关 键 词： | 黑米碳点 荧光性质 稳定性 细胞成像 |
| 收稿时间： | 2022/9/21 0:00:00 |
| 修稿时间： | 2023/3/15 0:00:00 |
Green synthesis of high-stability black rice carbon dots for application in cell imaging |
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| ZHANG Qing-Mei,ZHANG Lu-Peng,ZHENG Kai-Wen,YANG Guo-Qing,HE Song-Jie,DU Xiu-Juan,CHEN Feng-Hu,LI Bing.Green synthesis of high-stability black rice carbon dots for application in cell imaging[J].Chinese Journal of Inorganic Chemistry,2013,29(18). |
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| Authors: | ZHANG Qing-Mei ZHANG Lu-Peng ZHENG Kai-Wen YANG Guo-Qing HE Song-Jie DU Xiu-Juan CHEN Feng-Hu LI Bing |
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| Institution: | School of Applied Science, Taiyuan University of Science and Technology, Taiyuan 030024, China; Hospital of Stomatology, Shanxi Medical University, Taiyuan 030001, China |
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| Abstract: | Carbon dots (CDs) were synthesized by a facile hydrothermal method using cheap black rice as a carbon source. The synthesized CDs exhibited excellent stability, which was not sensitive to changes in temperature, pH, and solution of NaCl, and were immune to many metal ions. The purified CDs also had low cytotoxicity against human oral keratinocytes (Hok), cancer cells (cervical cancer, Hela), and bone marrow mesenchymal stem (BMSC, MC3T3) cells. Meanwhile, it behaved with excitation-independent behavior in the shorter wavelength range (410-470 nm) and excitation-dependent behavior in the longer wavelength range (470-510 nm). Due to the excellent fluo-rescence properties and stability, we applied them to the intracellular imaging of Hok, Hela, and MC3T3 cells. |
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| Keywords: | black rice carbon dots fluorescence properties stability cell imaging |
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