二价铜、锌离子对盐酸巴马亭与牛血清白蛋白结合反应光谱的影响研究 |
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引用本文: | 张立伟,杨频,王芳.二价铜、锌离子对盐酸巴马亭与牛血清白蛋白结合反应光谱的影响研究[J].无机化学学报,1999,15(4):545-548. |
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作者姓名: | 张立伟 杨频 王芳 |
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作者单位: | 山西大学分子科学研究所,太原,030006 |
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摘 要: | The binding of Palmatine hydrochloride to bovine serum albumin (BSA) was studied, in the presence of Cu2+ and Zn2+, with fluorescence spectrum and ultra-violet spectrum. The results show that Cu2+ and Zn2+ don′t influence the first binding constant of Palmatine to BSA and the binding site of it to BSA. But Cu2+ has the fluorescence quenching effect on sensitive fluorescence of medicine binding to BSA.
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关 键 词: | 盐酸巴马亭 牛血清白蛋白 铜离子 锌离子 光谱 |
修稿时间: | 1998-07-06 |
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