Potassium tert‐Butoxide Catalyzed Synthesis and Characterization of Novel 3‐Aryl‐3‐(phenylthio)‐1‐(thiophen‐3‐yl)propan‐1‐one Derivatives |
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Authors: | Yakup Budak |
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Institution: | Department of Chemistry, Faculty of Arts and Sciences, Gaziosmanpasa University, 60250, Tokat, Turkey |
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Abstract: | A series of thiophenyl‐containing 3‐thiophene derivatives ( 4a – 4i ) were prepared via the reaction of chalcone‐analogua compounds ( 3a – 3i ) and thiophenol in the presence of catalytic amount of KOBu‐t in CH2Cl2 with moderate to high yields. The mechanistic pathway of the reaction was explained by the Michael‐type addition of thiophenol to chalcone derivatives ( 3a – 3i ). |
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Keywords: | 1‐thiophen‐3‐yl)ethanone Michael addition potassiumtert‐butoxide chalcone catalysis |
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