Alum (KAl(SO4)2·12H2O) Catalyzed Multicomponent Transformation: Simple,Efficient, and Green Route to Synthesis of Functionalized Spiro[chromeno[2,3‐d]pyrimidine‐5,3′‐indoline]‐tetraones in Ionic Liquid Media |
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| Authors: | Mojtaba Mirhosseini Moghaddam Ayoob Bazgir Akhondi Mohammad Mehdi Ramin Ghahremanzadeh |
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| Institution: | 1. Nanobiotechnology Research Center, Avicenna Research Institute, ACECR, Tehran, Iran;2. Department of Chemistry, Shahid Beheshti University, Tehran, Iran;3. Reproductive Research Center, Avicenna Research Institute, ACECR, Tehran, Iran |
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| Abstract: | The combination of isatin, barbituric acid, and cyclohexane‐1,3‐dione derivatives in the presence of alum (KAl(SO4)2·12H2O) as a catalyst for 15 min was found to be a suitable and efficient method for the synthesis of spirochromeno2,3‐d]pyrimidine‐5,3′‐indoline]‐tetraones. |
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| Keywords: | isatin spirooxindoles dimedone barbituric acid ionic liquids |
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