| 4,5-二氢-1,2,4-三唑-5-硫酮席夫碱的合成和生物活性 |
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| 引用本文： | 孙晓红,白燕,刘源发,陈邦,贾英琦,曾振芳.4,5-二氢-1,2,4-三唑-5-硫酮席夫碱的合成和生物活性[J].中国化学,2009,27(7):1397-1400. |
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| 作者姓名： | 孙晓红 白燕 刘源发 陈邦 贾英琦 曾振芳 |
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| 作者单位： | College of Chemical Engineering, Chemical Research Institute, Northwest University, Xi’an, ;Shaanxi 710069, China ; Department of Chemistry, Northwest University, Xi’an, Shaanxi 710069, China ; |
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| 摘 要： | 以4-氨基-4,5-二氢-3-苯氧甲基-1氢-1,2,4-三唑-5-硫酮与取代苯甲醛为原料反应制得了9个新的三唑硫酮席夫碱类化合物，经IR、1H NMR和元素分析确定了各化合物结构。初步室内毒力测试结果表明该类化合物其具有较好的杀菌活性。
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| 关 键 词： | 三唑 席夫碱 合成 生物活性 |
| 收稿时间： | 2008-12-10 |
| 修稿时间： | 2009-2-11 |
Synthesis and Biological Activity of 4,5‐Dihydro‐1,2,4‐triazole‐5‐thione Schiff Base |
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| Xiaohong SUN,Yan BAI,Yuanfa LIU,Bang CHEN,Yingqi JIA,Zhenfang ZENG.Synthesis and Biological Activity of 4,5‐Dihydro‐1,2,4‐triazole‐5‐thione Schiff Base[J].Chinese Journal of Chemistry,2009,27(7):1397-1400. |
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| Authors: | Xiaohong SUN Yan BAI Yuanfa LIU Bang CHEN Yingqi JIA Zhenfang ZENG |
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| Abstract: | The 4,5‐dihydro‐1,2,4‐triazole Schiff base derivatives were synthesized with 4‐amino‐4,5‐dihydro‐3‐(phenoxy‐ methyl)‐1H‐1,2,4‐triazole‐5‐thione and substituted benzaldehydes. The chemical structures of the compounds have been confirmed by 1H NMR, IR spectra and elemental analysis. Their biological activities were investigated, and the results showed that they exhibited good fungicidal activities. |
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| Keywords: | triazole Schiff base synthesis biological activity |
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