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甘油单油酸脂/水立方液晶体系流变性质的研究
引用本文:水玲玲,王志宁,郑利强.甘油单油酸脂/水立方液晶体系流变性质的研究[J].中国化学,2005,23(3):245-250.
作者姓名:水玲玲  王志宁  郑利强
作者单位:KeyLaboratoryofColloidandInterfaceChemistryforMinistryofEducation,ShandongUniversity,Shandong,Jinan250100,China
摘    要:Monoglyceride (MO) can form various liquid crystalline phases spontaneously in the presence of various amount of water at room temperature. The appropriate compositions from binary phase diagram of MO/H2O were selected to form cubic phases. The selected systems were studied at different salt concentrations and pH value using rheological methods. There was a weak effect of salt on viscoelastic properties of cubic phases formed from MO/H2O system. Hexagonal phase was formed when pH value was decreased or increased. The viscoelasticity of cubic phases was different from that of hexagonal liquid crystals. Rheological properties of MO/H2O cubic phases were stable at pH and salt concentration similar to physiological condition.

关 键 词:流变学特性  甘油一酸酯  晶相  药物传输体系  稳定性  人体
收稿时间:2004-5-24
修稿时间:2004-11-8

Rheological Properties of Cubic Liquid Crystals Formed from Monoglyceride/H2O Systems
Shui Ling‐Ling,Wang Zhi‐Ning,Zheng Li‐Qiang.Rheological Properties of Cubic Liquid Crystals Formed from Monoglyceride/H2O Systems[J].Chinese Journal of Chemistry,2005,23(3):245-250.
Authors:Shui Ling‐Ling  Wang Zhi‐Ning  Zheng Li‐Qiang
Abstract:Monoglyceride (MO) can form various liquid crystalline phases spontaneously in the presence of various amount of water at room temperature. The appropriate compositions from binary phase diagram of MO/H2O were selected to form cubic phases. The selected systems were studied at different salt concentrations and pH value using rheological methods. There was a weak effect of salt on viscoelastic properties of cubic phases formed from MO/H2O system. Hexagonal phase was formed when pH value was decreased or increased. The viscoelasticity of cubic phases was different from that of hexagonal liquid crystals. Rheological properties of MO/H2O cubic phases were stable at pH and salt concentration similar to physiological condition.
Keywords:monoglyceride  rheological propert  viscoelasticity  cubic phase
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