| 尿素催化的高效绿色Knoevenagel缩合反应 |
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| 引用本文： | 孙崎,史兰香,葛泽梅,程铁明,李润涛.尿素催化的高效绿色Knoevenagel缩合反应[J].中国化学,2005,23(6):745-748. |
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| 作者姓名： | 孙崎 史兰香 葛泽梅 程铁明 李润涛 |
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| 作者单位： | SchoolofPharmaceuticalSciences,PekingUniversity,Beijing100083,China |
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| 摘 要： | An efficient and green procedure for the urea catalyzed Knoevenagel condensation was developed. In the presence of a catalytic ammount of urea, stoichiometric aldehyde and active methylene compound reacted under sol-vent-free conditions at 100℃ for 5-60 min to give nearly quantitative yield of product.
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| 关 键 词： | 尿素 催化合成反应 活性亚甲基 有机合成方法 清洁生产 环境保护 |
| 收稿时间： | 2004-9-20 |
| 修稿时间： | 2005-2-2 |
An Efficient and Green Procedure for the Knoevenagel Condensation Catalyzed by Urea |
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| Sun Qi,Shi Lan‐Xiang,Ge Ze‐Mei,Cheng Tie‐Ming,Li Run‐Tao.An Efficient and Green Procedure for the Knoevenagel Condensation Catalyzed by Urea[J].Chinese Journal of Chemistry,2005,23(6):745-748. |
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| Authors: | Sun Qi Shi Lan‐Xiang Ge Ze‐Mei Cheng Tie‐Ming Li Run‐Tao |
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| Abstract: | An efficient and green procedure for the urea catalyzed Knoevenagel condensation was developed. In the presence of a catalytic ammount of urea, stoichiometric aldehyde and active methylene compound reacted under solvent‐free conditions at 100 °C for 5‐60 min to give nearly quantitative yield of product. |
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| Keywords: | Knoevenagel condensation green procedure urea catalyst active methylene |
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