| Fabrication of CeO2 Nanoparticle Modified Glassy Carbon Electrode for Ultrasensitive Determination of Trace Amounts of Uric Acid in Urine |
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| 作者姓名： | 尉艳 李茂国 方宾 |
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| 作者单位： | [1]School of Chemistry and Materials Science, Anhui Normal University, Wuhu, Anhui 241000, China [2]Department of Chemistry, Wannan Medical College, Wuhu, Anhui 241000, China [3]Anhui Key Laboratory of Functional Molecular Solids, Wuhu, Anhui 241000, China |
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| 基金项目： | Project supported by the National Natural Science Foundation of China （No. 20675001）, Anhui Provincial Natural Science Foundation （No. 050460301） and the Science Foundation of Education 0ffice of Anhui Province （Nos. 2006kj145B and 2006kj119B）. |
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| 摘 要： | The preparation of a glassy carbon electrode modified by CeO2 nanoparticles was described, which was characterized by cyclic voltammetry and electrochemical impedance spectroscopy. In pH 6.0 buffer, the CeO2 nanoparticle modified electrode （CeO2 NP/GC） gave an excellent electrocatalytic activity for the oxidation of uric acid （UA）. The catalytic current of UA versus its concentration had a good linear relation in the range of 2.0 × 10^-7-5.0 × 10^- 4 mol/L, with the correlation coefficient of 0.9986 and detection limit of 1.0 ×10^-7 mol/L. The modified electrode can be used for the determination of UA in urine, which can tolerate the interference of ascorbic acid up to 1000-fold. The method was simple, quick and sensitive.
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| 关 键 词： | 电催化 氧化铈 纳米颗粒 修饰电极 尿酸 |
| 修稿时间： | 2006-09-18 |
Fabrication of CeO2 Nanoparticle Modified Glassy Carbon Electrode for Ultrasensitive Determination of Trace Amounts of Uric Acid in Urine |
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| WEI, Yan LI, Mao-Guo FANG,Bin.Fabrication of CeO2 Nanoparticle Modified Glassy Carbon Electrode for Ultrasensitive Determination of Trace Amounts of Uric Acid in Urine[J].Chinese Journal of Chemistry,2007,25(11):1622-1626. |
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| Authors: | WEI Yan LI Mao-Guo FANG Bin |
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| Institution: | 1 School of Chemistry and Materials Science, Anhui Normal University, Wuhu, Anhui 241000, China ;2 Department of Chemistry, Wannan Medical College, Wuhu, Anhui 241000, China ;3 Anhui Key Laboratory of Functional Molecular Solids, Wuhu, Anhui 241000, China |
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| Abstract: | The preparation of a glassy carbon electrode modified by CeO2 nanoparticles was described, which was characterized by cyclic voltammetry and electrochemical impedance spectroscopy. In pH 6.0 buffer, the CeO2 nanoparticle modified electrode (CeO2 NP/GC) gave an excellent electrocatalytic activity for the oxidation of uric acid (UA). The catalytic current of UA versus its concentration had a good linear relation in the range of 2.0×10−7−5.0×10−4 mol/L, with the correlation coefficient of 0.9986 and detection limit of 1.0×10−7 mol/L. The modified electrode can be used for the determination of UA in urine, which can tolerate the interference of ascorbic acid up to 1000-fold. The method was simple, quick and sensitive. |
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| Keywords: | electrocatalysis CeO2 nanoparticle modified electrode uric acid |
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