| 两个具有PTP1B抑制活性的4-羟基丁内酯化合物的全合成研究 |
| |
| 引用本文： | 赵亚,蒋晟,郭跃伟,姚祝军.两个具有PTP1B抑制活性的4-羟基丁内酯化合物的全合成研究[J].中国化学,2005,23(2):173-175. |
| |
| 作者姓名： | 赵亚 蒋晟 郭跃伟 姚祝军 |
| |
| 作者单位： | [1]StateKeyLaboratoryofDrugResearch,InstituteofMateriaMedica,ShanghaiInstituteforBiologicalSciences,ChineseAcademyofSciences,Shanghai201203,China [2]StateKeyLaboratoryofBioorganicandNaturalProductsChemistry,ShanghaiInstituteofOrganicChemistry,ChineseAcademyofSciences,Shanghai200032,China |
| |
| 摘 要： | Two new naturally 4-hydroxylated butenolides were concisely synthesized in excellent enantiomeric purities. An aldol condensation and a Suzuki reaction served successfully as the key steps in the synthesis.
|
| 关 键 词： | 合成 4-羟基丁烯羟酸内酯 PTPIB 抑制活性 Suzuki反应 丁间醇醛 |
| 收稿时间： | 2004-4-5 |
| 修稿时间： | 2004-11-12 |
Synthesis of Two Naturally Occurring 4‐Hydroxylated Butenolides with PTP1B Inhibitory Activity |
| |
| Zhao Ya,Jiang Sheng,Guo Yue‐Wei,Yao Zhu‐Jun.Synthesis of Two Naturally Occurring 4‐Hydroxylated Butenolides with PTP1B Inhibitory Activity[J].Chinese Journal of Chemistry,2005,23(2):173-175. |
| |
| Authors: | Zhao Ya Jiang Sheng Guo Yue‐Wei Yao Zhu‐Jun |
| |
| Abstract: | Two new naturally 4‐hydroxylated butenolides were concisely synthesized in excellent enantiomeric purities. An aldol condensation and a Suzuki reaction served successfully as the key steps in the synthesis. |
| |
| Keywords: | butenolide aldol condensation Suzuki reaction PTP 1B |
| 本文献已被 维普 等数据库收录！ |
| 点击此处可从《中国化学》浏览原始摘要信息 |
| 点击此处可从《中国化学》下载免费的PDF全文 |
