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Synthesis of polyamide containing pyrrole and imidazole amino acids |
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| Authors: | XIAO Jun-Hua HUANG Wei-Qiang TANG Fei-LiYUAN Gu |
| Institution: | XIAO,Jun-Hua HUANG,Wei-Qiang TANG,Fei-LiYUAN,GuDepartment of Chemistry,Laboratory of Bioorganic and Molecular Engineering,Peking University,Beijing 100871,ChinaCHAN,Alberts. C. LEE,K-L DanielOpen Laboratory of Chirotechnology and Department of Applied Biology and Chemical Technology,The Hong Kong Polytechnic University,Hong Kong,China |
| Abstract: | A polyainide containing N-methylpyrrole ( Py) and N-methylimidazole (Im) amino acids was synthesized by coupling two of the four-ring oligopeptide chains using DCC/ HOBT as promoting additives. The structure of the polyamide was confirmed by 1R, NMR and MS spectra. |
| Keywords: | DNA recognizing molecule polyamides synthesis |
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