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Ga(OTf)3-catalyzed Three-component Mannich Reaction in Water Promoted by Ultrasound Irradiation |
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| Authors: | ZHANG Guangliang HUANG Zhihao ZOU Jianping |
| Institution: | 1. Key Laboratory of Organic Synthesis of Jiangsu Province,College of Chemistry and Chemical Engineering,Suzhou University,Suzhou,Jiangsu 215123,China 2. Key Laboratory of Organic Synthesis of Jiangsu Province,College of Chemistry and Chemical Engineering,Suzhou University,Suzhou,Jiangsu 215123,China;Department of Chemical Research,Suzhou Yaomigu Co.Ltd,Suzhou,Jiangsu 215000,China |
| Abstract: | Ga(OTf)3‐catalyzed three‐component Mannich reaction of aromatic aldehydes, aromatic amines and cycloketones in water promoted by ultrasound gave the corresponding β‐amino cycloketones in good to excellent yields and good anti selectivities. |
| Keywords: | Ga(OTf)3 Mannich reaction multi-component reaction (MCR) β-amino cycloketone |
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