Transition Metal Free Chemoselective Reduction of α,β‐Unsaturated Ketones to Saturated Ketones Using Tosyl Hydrazide as a Hydrogen Donor |
| |
| Authors: | Yarabally R Girish Kanchipura R Raghavendra Dasappa Nagaraja Kothanahally S Sharath Kumar Sheena Shashikanth |
| |
| Institution: | 1. Deparment of Studies in Chemistry, Manasagangothri, University of Mysore, Mysore 570006, India;2. Department of PG Studies in Chemistry, Government Science College, Chitradurga 577501, India |
| |
| Abstract: | An efficient, inexpensive and simple method for the reduction of various α,β‐unsaturated ketones to corresponding saturated ketones using tosyl hydrazide as a hydrogen donor in DMF using calcium oxide powder has been reported. A variety of enones underwent reduction without forming undesirable side products. High chemoselectivity, broad functional group tolerance and good yields are the noteworthy features of this protocol. |
| |
| Keywords: | α β ‐unsaturated carbonyl compounds tosyl hydrazide transition metal free saturated ketones |
|
|
