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Study on Syntheses and Anti-bacterial Activities of Some New Transition Metal Complexes with Schiff Base Ligand Containing Pyridine and Amide Moieties
作者姓名:李美英  胡培植  朱军成  刘义  徐括喜
作者单位:DepartmentofChemistry,WuhanUniversity,Wuhan,Hubei430072,China
基金项目:Project supported by the National Natural Science Foundation of China (No. 20072029).
摘    要:Several new transition metal complexes using Schiff base containing pyridine and amide moieties (N, N′-bis(β-salicylaliminoethyl)-2, 6-pyridinedicarboxylic amide, H4L) as the ligand have been prepared. Their compositions and structures are corroborated by elemental analysis, IR, UV, ^1H NMR, DTA-TG and molar conductivity data.Their anti-bacterial activities have been studied by microcalorimetry. The result shows that the ligand and all complexes are potential anti-bacteria reagent and their inhibitory capacities are concentration-depended. The Mn complex has the strongest inhibitory capacity.

关 键 词:抗菌活性  转换金属复合物  嘧啶  半氨基化合物  席夫碱配合基

Study on Syntheses and Anti-bacterial Activities of Some New Transition Metal Complexes with Schiff Base Ligand Contain-ing Pyridine and Amide Moieties
LI,Mei-Ying HU,Pei-Zhi ZHU,Jun-Cheng LIU,Yi XU,Kuo-Xi.Study on Syntheses and Anti-bacterial Activities of Some New Transition Metal Complexes with Schiff Base Ligand Containing Pyridine and Amide Moieties[J].Chinese Journal of Chemistry,2004,22(2):162-166.
Authors:LI  Mei-Ying HU  Pei-Zhi ZHU  Jun-Cheng LIU  Yi XU  Kuo-Xi
Institution:LI,Mei-Ying HU,Pei-Zhi* ZHU,Jun-Cheng LIU,Yi XU,Kuo-XiDepartment of Chemistry,Wuhan University,Wuhan,Hubei 430072,China
Abstract:Several new transition metal complexes using Schiff base containing pyridine and amide moieties (N, N'-bis(- salicylaliminoethyl)-2, 6-pyridinedicarboxylic amide, H4L) as the ligand have been prepared. Their compositions and structures are corroborated by elemental analysis, IR, UV, 1H NMR, DTA-TG and molar conductivity data. Their anti-bacterial activities have been studied by microcalorimetry. The result shows that the ligand and all com-plexes are potential anti-bacteria reagent and their inhibitory capacities are concentration-depended. The Mn com-plex has the strongest inhibitory capacity.
Keywords:anti-bacterial activity  transition metal complex  Schiff base  pyridine
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