| 用硼酸作催化剂一锅法合成双（二氢化嘧啶酮-4-基）苯 |
| |
| 引用本文： | 屠树江, ,朱晓彤, ,房芳, ,章晓镜, ,朱松磊, ,李团结, ,史达清,王香善, ,纪顺俊.用硼酸作催化剂一锅法合成双（二氢化嘧啶酮-4-基）苯[J].中国化学,2005,23(5):596-598. |
| |
| 作者姓名： | 屠树江 朱晓彤 房芳 章晓镜 朱松磊 李团结 史达清 王香善 纪顺俊 |
| |
| 作者单位： | [1]KeyLaboratoryofOrganicSynthesisofJiangsuProvince,CollegeofChemistryandChemicalEngineering,SuzhouUniversity,Suzhou,Jiangsu215006,China [3]DepartmentofChemistry,XuzhouNormalUniversity,KeyLaboratoryofBiotechnologyonMedicalPlant,Xuzhou,Jiangsu221009,China |
| |
| 摘 要： | A simple effective synthesis of bis(dihydropyrimidinone-4-yl)benzene derivatives, using boric acid as catalyst,from isophthalic aldehyde or terephthalic aldehyde, 1,3-dicarbonyl compounds and urea or thiourea in glacial acetic acid was described. As the expansion of the classical Biginelli reaction, this method has the advantage of excellent yields 83%-94% and short reaction time 0.5-1.5 h.
|
| 关 键 词： | 合成方法 双（二氢嘧啶酮-4-基）苯 硼酸 催化剂 化学反应 |
| 收稿时间： | 2004-5-24 |
| 修稿时间： | 2005-1-24 |
One‐pot Synthesis of Bis(dihydropyrimidinone‐4‐yl)benzene Using Boric Acid as a Catalyst |
| |
| Tu Shu‐Jiang,Zhu Xiao‐Tong,Fang Fang,Zhang Xiao‐Jing,Zhu Song‐Lei,Li Tuan‐Jie,Shi Da‐Qing,Wang Xiang‐Shan,Ji Shun‐Jun.One‐pot Synthesis of Bis(dihydropyrimidinone‐4‐yl)benzene Using Boric Acid as a Catalyst[J].Chinese Journal of Chemistry,2005,23(5):596-598. |
| |
| Authors: | Tu Shu‐Jiang Zhu Xiao‐Tong Fang Fang Zhang Xiao‐Jing Zhu Song‐Lei Li Tuan‐Jie Shi Da‐Qing Wang Xiang‐Shan Ji Shun‐Jun |
| |
| Abstract: | A simple effective synthesis of bis(dihydropyrimidinone‐4‐yl)benzene derivatives, using boric acid as catalyst, from isophthalic aldehyde or terephthalic aldehyde, 1,3‐dicarbonyl compounds and urea or thiourea in glacial acetic acid was described. As the expansion of the classical Biginelli reaction, this method has the advantage of excellent yields 83%–94% and short reaction time 0.5–1.5 h. |
| |
| Keywords: | dihydropyrimidinone dialdehyde Biginelli urea |
| 本文献已被 维普 等数据库收录！ |
| 点击此处可从《中国化学》浏览原始摘要信息 |
| 点击此处可从《中国化学》下载免费的PDF全文 |
|
