Computer Simulation of Non-Newtonian Flow and Mass Transport Through Coronary Arterial Stenosis

A numerical analysis of Newtonian and non_Newtonian flow in an axi_symmetric tube with a local constriction simulating a stenosed artery under steady and pulsatile flow conditions was carried out. Based on these results, the concentration fields of LDL (low_density lipoprotein) and Albumin were discussed. According to the results, in great details the macromolecule transport influences of wall shear stress, non_Newtonian fluid character and the scale of the molecule etc are given. The results of Newtonian fluid flow and non_Newtonian fluid flow, steady flow and pulsatile flow are compared. These investigations can provide much valuable information about the correlation between the flow properties, the macromolecule transport and the development of atherosclerosis.