| BLOOD FLOW AND MACROMOLECULAR TRANSPORT IN CURVED BLOOD VESSELS |
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| 作者姓名： | 魏兰 温功碧 谭文长 |
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| 作者单位： | Department of Mechanics and Engineering Science State Key Laboratory for Turbulence and Complex System Peking University Beijing 100871 P. R. China，Institute of Applied Physics and Computational Mathematics Beijing 100088 P. R. China，Department of Mechanics and Engineering Science State Key Laboratory for Turbulence and Complex System Peking University Beijing 100871 P. R. China，Department of Mechanics and Engineering Science State Key Laboratory for Turbulence and Complex System Peking University Beijing 100871 P. R. China |
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| 摘 要： | A numerical analysis of the steady/pulsatile flow and macromolecular (such as LDL and Albumin) transport in curved blood vessels was carried out. The computational results predict that the vortex of the secondary flow is time-dependent in the aortic arch. The concentration of macromolecule concentrates at the region of sharp curve, and the wall concentration at the outer part is higher than that at the inner part. Atherosclerosis and thrombosis are prone to develop in such regions with sharp flow.
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| 关 键 词： | 弯曲血管 血流 宏观分子转移 动脉硬化症 |
| 文章编号： | 10.1007/s10483-006-0909-y |
| 收稿时间： | 2004-06-30 |
| 修稿时间： | 2006-04-27 |
Blood flow and macromolecular transport in curved blood vessels |
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| Lan Wei,Gong-bi Wen,Wen-chang Tan.BLOOD FLOW AND MACROMOLECULAR TRANSPORT IN CURVED BLOOD VESSELS[J].Applied Mathematics and Mechanics(English Edition),2006,27(9):1223-1231. |
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| Authors: | Lan Wei Gong-bi Wen Wen-chang Tan |
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| Institution: | 1. Department of Mechanics and Engineering Science, State Key Laboratory for Turbulence and Complex System, Peking University, Beijing 100871, P. R. China;Institute of Applied Physics and Computational Mathematics, Beijing 100088, P. R. China
2. Department of Mechanics and Engineering Science, State Key Laboratory for Turbulence and Complex System, Peking University, Beijing 100871, P. R. China |
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| Abstract: | A numerical analysis of the steady/pulsatile flow and macromolecular (such as LDL and Albumin) transport in curved blood vessels was carried out. The computational results predict that the vortex of the secondary flow is time-dependent in the aortic arch. The concentration of macromolecule concentrates at the region of sharp curve, and the wall concentration at the outer part is higher than that at the inner part. Atherosclerosis and thrombosis are prone to develop in such regions with sharp flow. |
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| Keywords: | curved blood vessels blood flow macromolecular transport atherosclerosis |
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