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组合荷载下超大群桩受力变形模型试验研究
引用本文:廖东华,高松,曾衍钧,刘有军,杨坚,赵静波,L.Vinter-Jensen,H.Gregersen.组合荷载下超大群桩受力变形模型试验研究[J].力学学报,2004,36(2):171-176.
作者姓名:廖东华  高松  曾衍钧  刘有军  杨坚  赵静波  L.Vinter-Jensen  H.Gregersen
作者单位:北京工业大学生物力学与医学信息研究所, 北京 100022
基金项目:国家自然科学基金(10072006)~~
摘    要:研究表皮生长因子(EGF)2,4,7,14d处理后鼠小肠所发生的生物力学重建. 通 过双轴试验(膨胀与轴向拉伸组合),用最小二乘法计算了近于在体状态下环向、纵向及交 叉向增量杨氏模量. 各组环向和纵向模量均不相等,即正常状态和EGF处理后的小肠是各向 异性的. 在EGF处理期间,各向的杨氏模量随时间变化(P<0.05). 在EGF处理的最 初7d中,环向模量减小,在处理14d后,又恢复到对照组的水平. 增量模量介 于17.4kPa与24.2kPa 之间. 纵向模量的值介于22.9kPa与32.4kPa之间,在处理4d后,比对照值显著增大(P<0.02). 交叉模量的值介于4.7kPa与6.6kPa之间,在最初EGF处理的4d中降低,此后增加并 于第7d达到最大值. 可以得出结论,肠壁的力学性质呈各向异性且在EGF处理期间会发生重建.

关 键 词:李子沟特大桥  模型试验  群桩  组合荷载
收稿时间:2003-12-09
修稿时间:2003年5月22日

The incremental Young's moduli in the rat small intestine caused by
Liao Donghua Gao Song Zeng Yanjun Liu Youjun,Yang Jian Zhao Jingbo L.Vinter-Jensen H.Gregersen.The incremental Young''s moduli in the rat small intestine caused by[J].chinese journal of theoretical and applied mechanics,2004,36(2):171-176.
Authors:Liao Donghua Gao Song Zeng Yanjun Liu Youjun  Yang Jian Zhao Jingbo LVinter-Jensen HGregersen
Institution:1. College of Civil Engineering, Southwest Jiaotong University, Chengdu 610031; 2. Bridge and Tunnel Department, The 2 nd Railway Survey &;|Design Institute, Chengdu 610031
Abstract:Biomechanical remodelling of the rat small intestine after treatment with epidermal growth factor (EGF) subcutaneously for 2 days (n-6),4 days (n=6),7 days (n=6),and 14 days (n=4) was studied.The incremental circumferential,longitudinal and cross moduli close to the in vivo state were computed from bi-axial test data (combined inflation and axial stretching) by a least square method.The moduli in the circumferential direction and the longitudinal direction differed in all groups,i.e.the mechanical properties were anisotropic in both normal and EGF-treated rats.Time-dependent variation existed for the Young's moduli in all directions during EGF treatment (P<0.05).The circumferential modulus decreased during the first 7 days of EGF treatment and it almost remodelled back to that of the control group after 14 days treatment.The incremental modulus in the circumferential direction ranged between 17.4 kPa and 24.2 kPa.The modulus in the longitudinal direction ranged between 22.9kPa and 32.4 kPa.The longitudinal modulus after 4 days EGF treatment was significantly larger than that of control group (P<0.02).The cross modulus decreased during the first 4 days of EGF treatment thereafter it increased to a maximum at 7 days.The values for the cross moduli were between 4.7 kPa and 6.6 kPa.In conclusion,the mechanical properties in the intestinal wall are anisotropic and remodel during treatment with EGF.
Keywords:EGF treatment  small intestine  Young's modulus  anisotropy
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