| 血管内皮细胞糖萼与力传导 |
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| 引用本文： | 邓小燕,康红艳.血管内皮细胞糖萼与力传导[J].力学与实践,2010,32(1):1-9. |
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| 作者姓名： | 邓小燕 康红艳 |
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| 作者单位： | 北京航空航天大学生物与医学工程学院，北京 100083 北京航空航天大学生物与医学工程学院，北京 100083 |
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| 摘 要： | 血管内皮细胞糖萼是位于内皮细胞顶膜的一层绒毛状多糖蛋白复合结构,是血管壁的选择性通透屏障.主要在协助红细胞顺利通过毛细血管、抑制血细胞对内皮的粘附及信号传递等过程中发挥重要的生理作用.大量研究证据表明糖萼可能还参与了内皮细胞对剪切力的感受和传导.在简要介绍了糖萼的结构及生理功能的基础上,本文着重对糖萼在力传导方面的研究进展进行了综述.
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| 关 键 词： | 糖萼 力传导 内皮细胞 |
| 收稿时间： | 2009-03-05 |
GLYCOCALYX AND MECHANOTRANSDUCTION |
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| DENG Xiaoyan
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KANG Hongyan.GLYCOCALYX AND MECHANOTRANSDUCTION[J].Mechanics and Engineering,2010,32(1):1-9. |
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| Authors: | DENG Xiaoyan KANG Hongyan |
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| Institution: | 1;Department of Bioengineering/a>;Beihang University/a>;Beijing 100191/a>;China |
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| Abstract: | Glycocalyx on the surface of vascular endothelial cells is of a hair-like structure composed of various proteoglycans and glycoproteins and is a barrier with selective permeability for the vascular wall.It has been known that glycocalyx can assist red blood cells in their motion through capillaries,prevent the adhesion of blood cells and participate in signal communications.It has been well documented that glycocalyx may also take part in shear stress sensing and transduction.This article briefly reviews th... |
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| Keywords: | glycocalyx mechanotransduction endothelial cell |
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