A comparison between different asymmetric abdominal aortic aneurysm morphologies employing computational fluid–structure interaction analysis |
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| Institution: | 1. Endovascular Division of Cordis Corporation, a Johnson & Johnson Company, Warren, NJ 07059, USA;2. Department of Mechanical and Aerospace Engineering and Department of Biomedical Engineering, North Carolina State University, Raleigh, NC 27695-7910, USA;1. Faculty of Medicine and Health Sciences, Macquarie University, Sydney, NSW 2109, Australia;2. School of Mechanical and Manufacturing Engineering, The University of New South Wales, Sydney, NSW 2052, Australia;3. School of Management, Macquarie University, Sydney, NSW 2109, Australia;1. Department of Chemical Engineering, Imperial College London, South Kensington Campus, London SW7 2AZ, UK;2. Department of Surgery and Cancer, St. Mary’s Hospital, Imperial College London, UK;3. MRC London Institute of Medical Sciences, Hammersmith Hospital, Imperial College London, UK;4. Royal Brompton and Harefield NHS Foundation Trust, Sydney Street, London SW3 6NP, UK;1. Vascular Engineering Laboratory, Harry Perkins Institute of Medical Research, QEII Medical Centre, and Centre for Medical Research, The University of Western Australia, Perth, Australia;2. School of Mechanical and Chemical Engineering, The University of Western Australia, Perth, Australia;3. School of Surgery, The University of Western Australia, Perth, Australia;4. Vascular Surgery Research Group, Imperial College London, UK;5. BHF Centre for Cardiovascular Science, University of Edinburgh, UK;1. Guangdong Provincial Key Laboratory of Medical Biomechanics, Department of Anatomy, School of Basic Medicine Science, Southern Medical University, Guangzhou Dadao North Road 1838, Guangzhou 510515, PR China;2. Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, 1068 Xueyuan Boulevard, Xili Nanshan, Shenzhen 518055, PR China;3. School of Computer Science and Software Engineering, The University of Western Australia, 35 Stirling Highway, Crawley 6009, WA, Australia |
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| Abstract: | Considering representative asymmetric aneurysms in the abdominal aorta, the transient 3-D blood flow and pressure distributions as well as aneurysm wall stresses were numerically analyzed. To obtain more realistic and accurate results for blood flow fields and wall stress distributions, a coupled fluid-flow and solid–structure solver was employed. Geometric abdominal aortic aneurysm (AAA) variations studied included the degree of asymmetry, neck angle and bifurcation angle, and hence their impacts on the hemodynamics and biomechanics. The simulation results indicated that the assumption of symmetric AAA geometry may underestimate AAA-wall stress considerably. The neck angle influences the blood flow field substantially. A large neck angle, resulting in strong wall curvatures near the proximal neck, can produce aggravating blood flow patterns and elevated wall stresses (Von Mises). The iliac bifurcation angle affects blood flow patterns insignificantly but plays an important role in wall-stress concentrations. The wall stress of lateral asymmetric AAAs is higher than for the anterior-posterior asymmetric types. The maximum wall stress-site is located near the anterior distal side for the anterior-posterior asymmetric AAA and the distal side towards the asymmetric bulge in the lateral asymmetric AAA. |
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