Low-field nuclear magnetic resonance spectrometer for non-invasive monitoring of fluctuations in blood glucose in the human finger |
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| Authors: | Rongsheng Lu Jianxiong Hu Yi Chen Yuchen Wu Zhonghua Ni |
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| Institution: | 1. Jiangsu Key Laboratory for Design and Manufacture of Micro-Nano Biomedical Instruments, Southeast University, Nanjing, P. R. China;2. School of Mechanical Engineering, Southeast University, Nanjing, P. R. Chinalurs@seu.edu.cn;4. School of Mechanical Engineering, Southeast University, Nanjing, P. R. China |
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| Abstract: | A low-field nuclear magnetic resonance spectrometer for non-invasive monitoring of human finger blood glucose fluctuations was developed. Saline solution and blood serum samples with different glucose concentrations were first detected by the spectrometer and it has been found that there was a high-linear correlation between the glucose concentration and the transverse relaxation time. Then, the spectrometer was employed to noninvasively measure a finger from each of the several volunteers. The experiment results showed that the transverse relaxation time of the human finger increases with human blood glucose concentration. In conclusion, the human finger nuclear magnetic resonance spectrometer could be a potential tool to noninvasive monitoring of human body’s blood glucose fluctuations in the future. |
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| Keywords: | blood glucose non-invasive nuclear magnetic resonance permanent magnet |
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