| Dynamical Properties of Potassium Ion Channels with a Hierarchical Model |
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| 作者姓名： | 展永 安海龙 于慧 张素花 韩英荣 |
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| 作者单位： | School of Sciences, Hebei University of Technology, Tianjin 300130 |
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| 基金项目： | Supported by the National Natural Science Foundation of China under Grant Nos 10474018 and 10375016, the Hebei Provincial Natural Science Foundation under Grant Nos C2005000011 and A2004000005, the Subsidization for Construction Programme of Key Subjects in Universities and Colleges of Hebei Province, and the Hebei Provincial Doctoral Foundation under Grant No 2006148. |
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| 摘 要： | It is well known that potassium ion channels have higher permeability than K ions, and the permeable rate of a single K ion channel is about 108 ions per second. We develop a hierarchical model of potassium ion channel permeation involving ab initio quantum calculations and Brownian dynamics simulations, which can consistently explain a range of channel dynamics. The results show that the average velocity of K ions, the mean permeable time of K ions and the permeable rate of single channel are about 0.92nm/ns, 4.35ns and 2.30 ×10^8 ions/s, respectively.
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| 关 键 词： | 动力 钾离子通道 分级模型 量子计算 |
| 收稿时间： | 2006-06-21 |
| 修稿时间： | 2006-06-21 |
Dynamical Properties of Potassium Ion Channels with a Hierarchical Model |
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| ZHAN Yong, AN Hai-Long, YU Hui, ZHANG Su-Hua, HAN Ying-Rong.Dynamical Properties of Potassium Ion Channels with a Hierarchical Model[J].Chinese Physics Letters,2006,23(11):2906-2908. |
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| Authors: | ZHAN Yong AN Hai-Long YU Hui ZHANG Su-Hua HAN Ying-Rong |
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