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Image Restoration Phase-Filtering Lateral Superresolution Confocal Microscopy
作者姓名:赵维谦  邱丽荣  陈珊珊  冯政德
作者单位:Department of Automation Measurement and Control Engineering, Harbin Institute of Technology, Harbin 150001
基金项目:Supported by the National Natural Science Foundation of China under Grant No 50475035, and the Research Fund for the Doctoral Programme of Higher Education of China under Grant No 20050213035.
摘    要:Image restoration phase-filtering lateral superresolution confocal microscopy, a new approach, is proposed to achieve lateral superresolution using a confoeal microscope. This approach uses a lateral superresolution pupil filter to preliminarily improve its lateral resolution and uses a siagle-image superresolution restoration technique based on a maximum likelihood estimate to further improve its lateral resolution. The new approach has the advantages of a low cost and the remarkable superresolution effect without excessive system complexity. Experiments indicate that the proposed approach can improve the lateral resolution of a confocal microscope from 0.3μm to less than 0.1 μm when λ = 632.8 nm and NA=0.85.

关 键 词:图像恢复  相滤波  共焦显微术  信息光学
收稿时间:2005-12-20
修稿时间:2005-12-20

Image Restoration Phase-Filtering Lateral Superresolution Confocal Microscopy
ZHAO Wei-Qian, QIU Li-Rong, CHEN Shan-Shan, FENG Zheng-De.Image Restoration Phase-Filtering Lateral Superresolution Confocal Microscopy[J].Chinese Physics Letters,2006,23(4):856-859.
Authors:ZHAO Wei-Qian  QIU Li-Rong  CHEN Shan-Shan  FENG Zheng-De
Abstract:
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