Ion-molecule reactions of 2-methoxyethanol with some amines, carboxylic acids and amino acids under chemical ionization conditions

2-Methoxyethanol chemical ionization of amines, carboxylic acids and amino acids has been found to produce numerous adduct ions. The most intense adduct ions for amines are M + H](+) and M + 77](+), for carboxylic acids M + 27](+), M + 59](+) and M + 77](+), and for amino acids M + H](+), M + 13](+), M + 27](+) and M + 77](+). Either the adduct ion M + H](+) or M + 77](+) was the most abundant ion found for amino acids. The proton affinities of amino acids are noticed to control the formation of the M + H](+) and M + 77](+) ions. The relative abundance of M + 13](+) and M + 27](+) ions varied for different amino acids being most intense for phenylalanine and aspartic acid. Copyright 1999 John Wiley & Sons, Ltd.