| 水下强声频率对巴马小型猪肺脏病理损伤效应的观察 |
| |
| 引用本文： | 张纪铃,黄海宁,王建民,刘崇磊,曾玲.水下强声频率对巴马小型猪肺脏病理损伤效应的观察[J].声学学报,2019,44(4):796-803. |
| |
| 作者姓名： | 张纪铃 黄海宁 王建民 刘崇磊 曾玲 |
| |
| 作者单位： | 1. 中国科学院声学研究所 北京 100190; |
| |
| 基金项目： | 基金项目(Y7Z3091211)资助 |
| |
| 摘 要： | 为探索大功率水声信号对入水哺乳动物肺脏的生物效应,以佩戴专用水下呼吸装置的巴马小型猪为实验对象,采用大功率连续声波为暴露手段,对水下正常体征状态的小型猪进行强声辐射,通过大体解剖、HE染色显微病理图像观察等方法,分析水下强声对哺乳动物肺脏器官的损伤效应。在300 Hz^10 kHz的正弦频段中,当声压级大于190 dB时,出现了不同程度的肺脏损伤。大功率水声信号对入水哺乳动物肺脏的生物效应显著,在相同声压级条件下,3 kHz水下连续波对实验动物肺脏病理损伤效应最大。
|
| 关 键 词： | 水下强声 频率 损伤效应 肺脏 |
| 收稿时间： | 2018-10-23 |
Observation of pathological injury effect of underwater intense sound on lung of Bama miniature pig |
| |
| Institution: | 1. Institute of Acoustics, Chinese Academy of Sciences Beijing 100190;2. Key Laboratory of Advanced Underwater Information Technology, Chinese Academy of Sciences Beijing 100190;3. University of Chinese Academy of Sciences Beijing 100049;4. Key Laboratory of Underwater Acoustic Antagonism Zhanjiang 524000;5. Institute of Field Surgery, Daping Hospital, Third Military Medical University Chongqing 404100 |
| |
| Abstract: | In order to explore the biological effects of high-power underwater acoustic signals on the lungs of waterentering mammals,taking Bama miniature pig with special underwater breathing device as the experimental object,high-power continuous acoustic wave as the means of exposure was adopted to carry out intense acoustic radiation on the miniature pig with normal signs under water.The injury effect of underwater intense sound on the lung organ of mammals was analyzed Sby means of gross anatomy and observation of micro-pathological images with HE staining.In the sinusoidal band of 300~10 kHz,when the sound pressure level is higher than 190 dB,lung injury of different degrees occurs.The biological effect of high-power underwater acoustic wave on the lungs of entering mammals was significant.Under the same sound pressure level,underwater continuous wave of 3 kHz had the largest effect on pathological injury to the lungs of experimental animals. |
| |
| Keywords: | |
|
| 点击此处可从《声学学报》浏览原始摘要信息 |
| 点击此处可从《声学学报》下载免费的PDF全文 |
|
