首页 | 本学科首页   官方微博 | 高级检索  
     检索      


Quasispecies distribution of Eigen model
Authors:Chen Ji  Li Sheng and Ma Hong-Ru
Institution:Department of Physics, Shanghai Jiaotong University, Shanghai 200240, China
Abstract:We have studied sharp peak landscapes of the Eigen model from a new perspective about how the quasispecies are distributed in the sequence space. To analyse the distribution more carefully, we bring in two tools. One tool is the variance of Hamming distance of the sequences at a given generation. It not only offers us a different avenue for accurately locating the error threshold and illustrates how the configuration of the distribution varies with copying fidelity $q$ in the sequence space, but also divides the copying fidelity into three distinct regimes. The other tool is the similarity network of a certain Hamming distance $d_{0}$, by which we can gain a visual and in-depth result about how the sequences are distributed. We find that there are several local similarity optima around the centre (global similarity optimum) in the distribution of the sequences reproduced near the threshold. Furthermore, it is interesting that the distribution of clustering coefficient $C(k)$ follows lognormal distribution and the curve of clustering coefficient $C$ of the network versus $d_{0}$ appears to be linear near the threshold.
Keywords:Eigen model  sharp peak landscapes  similarity network  clustering coefficient
本文献已被 维普 等数据库收录!
点击此处可从《中国物理 B》浏览原始摘要信息
点击此处可从《中国物理 B》下载免费的PDF全文
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号