| 12C6+离子辐照小鼠Lewis肿瘤的研究 |
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| 引用本文： | 李文建,郭红云,李德杏,党秉荣,马秋峰,周利斌,王潇,郝冀芳,毛淑红.12C6+离子辐照小鼠Lewis肿瘤的研究[J].原子核物理评论,2003,20(4):281-283. |
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| 作者姓名： | 李文建 郭红云 李德杏 党秉荣 马秋峰 周利斌 王潇 郝冀芳 毛淑红 |
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| 作者单位： | 中国科学院近代物理研究所 甘肃兰州; 甘肃兰州730050; |
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| 基金项目： | 中国科学院院长特别支持基金资助项目(TB990601) |
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| 摘 要： | 研究了HIRFL提供的12C6+离子辐照C57BL/6J小鼠右后腿移植的Lewis肿瘤的生长延迟和碳离子辐照对Lewis肿瘤小鼠寿命的延长.结果表明,碳离子照射的小鼠肿瘤生长体积明显地小于对照的体积.在剂量相同、分次数辐照越多时,肿瘤生长就越缓慢,肿瘤抑制就越高.在辐照分次数相同时,不同剂量对受照肿瘤生长体积未产生差异.在4Gy×3,8Gy×3和12Gy×2组3种辐照剂量下,小鼠寿命的P值小于0.05;可知小鼠的寿命延长具有统计学意义. Growth delay of the transplantable Lewis tumors growing in right hind legs of C(57) BL/6J mice and life prolongation of the mice with Lewis tumors were investigated after()~(12)C~(6+) ion radiation at HIRFL. The results show that growth volumes of the mouse tumors following carbon radiation are distinctly less than control during 21 days; the more fractions of radiation with same doses, the slower growth of tumors and the higher inhibition of tumors; different doses with the same fractions of radiation ...
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| 关 键 词： | 12C6+离子 小鼠肿瘤 生长延迟 小鼠寿命 |
| 文章编号： | 1007-4627(2003)04-0281-03 |
| 收稿时间： | 1900-01-01 |
| 修稿时间： | 2003年5月21日 |
Study of Mouse Lewis Tumors by 12C6+ Ion Radiation |
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| Institution: | 1 Institute of Modern Physics; Chinese Academy of Sciences; Lanzhou 730000; China; 2 Gansu Academy of Medical Sciences; Lanzhou 730050; China |
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| Abstract: | Growth delay of the transplantable Lewis tumors growing in right hind legs of C(57) BL/6J mice and life prolongation of the mice with Lewis tumors were investigated after()~(12)C~(6+) ion radiation at HIRFL. The results show that growth volumes of the mouse tumors following carbon radiation are distinctly less than control during 21 days; the more fractions of radiation with same doses, the slower growth of tumors and the higher inhibition of tumors; different doses with the same fractions of radiation... |
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