生物组织光传播的时域特征分析

采用蒙特卡罗方法对脉冲光在组织中传播的时域特征作了研究，并把计算结果与漫射理论的解析解作了比较，文中详细分析了组织光学特性参数与组织表面时间分辨的漫反射光分布之间的关系。结果表明：散射系影响着漫反射光强到达峰值的时间，吸收系数影响着漫反射光强在峰值之后随时间下降的速度，而ｇ因子对响应曲线的前沿影响较大，在后沿阶段基本上没有影响。

Time Domain Characteristics of Light Propagation in Tissue

The time resolved Monte Carlo method is used to study the time domain characteristics of light pulse propagation in tissue. The simulation results of Monte Carlo method are compared with the analytic results of diffuse theory. The relation between the optical parameters of tissue and the time resolved reflectance on tissue surface is discussed. The results illustrate that the time of maximum reflectance is mainly affected by the scattering coefficient, the slope of the reflectance decrease is mainly affected by the absorption coefficient. The g factor only affects the early data of the time resolved reflectance. The results in this paper show more promise to apply in the noninvasive measurement of the optical parameters of tissue and the oxygen saturation in arterial and skeletal muscle.