| 可见-近红外反射光谱用于疾病快速筛查 |
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| 引用本文： | 李刚,赵静,李家星,林凌,张宝菊.可见-近红外反射光谱用于疾病快速筛查[J].光学学报,2011(3):191-196. |
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| 作者姓名： | 李刚 赵静 李家星 林凌 张宝菊 |
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| 作者单位： | 天津大学精密测试技术及仪器国家重点实验室;天津科技大学海洋科学与工程学院;天津师范大学物理与电子信息学院; |
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| 基金项目： | 国家自然科学基金(30973964); 天津市应用基础及其前沿技术研究计划(10JCYBJC00400)资助课题 |
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| 摘 要： | 为了探讨基于舌诊的疾病快速筛查,运用可见和近红外光谱仪,采集149名志愿者舌尖的反射光谱并且进行反射率归一化处理.根据临床诊断结果将样本分为4组:健康组、高粘血症倾向组、脂肪肝患者组和冠心病患者组.运用主成分分析(PCA)结合人工神经网络(ANN)方法、偏最小二乘(PLS)方法和间隔偏最小二乘(iPLS)方法3种方法建...
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| 关 键 词： | 光谱学 疾病诊断 主成分分析 人工神经网络 偏最小二乘法 间隔偏最小二乘法 |
Visible-Infrared Reflectance Spectroscopy Applied in Rapid Screen of Diseases |
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| Li Gang Zhao Jing Li Jiaxing, Lin Ling Zhang Baoju.Visible-Infrared Reflectance Spectroscopy Applied in Rapid Screen of Diseases[J].Acta Optica Sinica,2011(3):191-196. |
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| Authors: | Li Gang Zhao Jing Li Jiaxing Lin Ling Zhang Baoju |
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| Institution: | Li Gang1 Zhao Jing1 Li Jiaxing1,2 Lin Ling1 Zhang Baoju3(1State Key Laboratory of Precision Measurement Technology and Instruments,Tianjin University,Tianjin 300072,China2College of Marine Science and Engineering,Tianjin Uinversity of Science and Technology,China3College of Physics and Electronic Information,Tianjin Normal University,Tianjin 300387,China) |
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| Abstract: | To screen disease which based on tongue inspection rapidly,the reflection spectrum on the tongue tips of 149 volunteers were collected by visible and near-infrared spectrometer and then the normalized reflectivity was calculated.Samples were divided into four classes according to the clinical diagnosis information: healthy,hyperviscosity,fatty liver,and coronary heart disease groups.Spectra were then subjected to three different analysis methods: principle component analysis(PCA) combined with artificial ne... |
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| Keywords: | spectroscopy disease diagnosis principal component analysis(PCA) artificial neural network(ANN) partial least square(PLS) interval partial least square(iPLS) |
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